Find out why Effexor XR is prescribed, Effexor XR side effects, Effexor XR warnings, effects of Effexor XR during pregnancy, more - in plain English.

Generic name: Venlafaxine hydrochloride
Other brand name: Effexor XR

Pronounced: ef-ECKS-or

Effexor (venlafaxin) XR Full Prescribing Information

Why is Effexor XR prescribed?

Effexor is prescribed for the treatment of depression--that is, a continuing depression that interferes with daily functioning. The symptoms usually include changes in appetite, sleep habits, and mind/body coordination, decreased sex drive, increased fatigue, feelings of guilt or worthlessness, difficulty concentrating, slowed thinking, and suicidal thoughts.

Effexor XR is also prescribed to relieve abnormal anxiety (generalized anxiety disorder). This problem is marked by persistent anxiety for a period of at least 6 months, accompanied by at least 3 of these 6 symptoms: restlessness, fatigue, poor concentration, irritability, muscle tension, and sleep disturbances.

Effexor must be taken 2 or 3 times daily. The extended-release form, Effexor XR, permits once-a-day dosing.

Most important fact about Effexor XR

Serious, sometimes fatal reactions have occurred when Effexor is used in combination with other drugs known as MAO inhibitors, including the antidepressants Nardil and Parnate. Never take Effexor with one of these drugs; and do not begin therapy with Effexor within 14 days of discontinuing treatment with one of them. Also, allow at least 7 days between the last dose of Effexor and the first dose of an MAO inhibitor.

How should you take Effexor XR?

Take Effexor with food, exactly as prescribed. It may take several weeks before you begin to feel better. Your doctor should check your progress periodically.

Take Effexor XR once at the same time each day. Swallow the capsule whole with water. Do not divide, crush, or chew it.

 

--If you miss a dose...

It is not necessary to make it up. Skip the missed dose and continue with your next scheduled dose. Do not take 2 doses at once.

--Storage instructions...

Store in a tightly closed container at room temperature. Protect from excessive heat and moisture.

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What side effects may occur with Effexor XR?

Side effects cannot be anticipated. If any develop or change in intensity, tell your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Effexor.

• More common Effexor XR side effects may include: Abnormal dreams, abnormal ejaculation or orgasm, anxiety, appetite loss, blurred vision, chills, constipation, diarrhea, dizziness, dry mouth, frequent urination, flushing, gas, headache, impotence, infection, insomnia, muscle tension, nausea, nervousness, rash, sleepiness, sweating, tingling feeling, tremor, upset stomach, vomiting, weakness, yawning

• Less common side effects may include: Abnormal taste, abnormal thinking, agitation, chest pain, confusion, decreased sex drive, depression, dilated pupils, dizziness upon standing up, high blood pressure, itching, loss of identity, rapid heartbeat, ringing in the ears, trauma, twitching, urinary problems, weight loss

A wide variety of very rare symptoms possibly related to Effexor have also been reported. If you develop any new or unusual problems, let your doctor know about it.

Why should Effexor XR not be prescribed?

Never take Effexor while taking other drugs known as MAO inhibitors. (See "Most important fact about this drug.") Also avoid this drug if it has ever given you an allergic reaction.

Special warnings about Effexor XR

Your doctor will prescribe Effexor with caution if you have high blood pressure, heart, liver, or kidney disease or a history of seizures or mania (extreme agitation or excitability). You should discuss all of your medical problems with your doctor before taking Effexor.

Effexor sometimes causes an increase in blood pressure. If this happens, your doctor may need to reduce your dose or discontinue the drug.

Effexor also tends to increase the heart rate, especially at higher doses. Use Effexor with caution if you've recently had a heart attack, suffer from heart failure, or have an overactive thyroid gland.

Antidepressants such as Effexor may cause fluid retention, especially if you are an older adult.

Effexor may cause you to feel drowsy or less alert and may affect your judgment. Therefore, avoid driving or operating dangerous machinery or participating in any hazardous activity that requires full mental alertness until you know how this drug affects you.

Your doctor will check you regularly if you have glaucoma (high pressure in the eye), or you are at risk of developing it.

If you have ever been addicted to drugs, tell your doctor before you start taking Effexor.

If you develop a skin rash or hives while taking Effexor, notify your doctor. Effexor may also cause bleeding or bruising of the skin.

Do not stop taking the drug without consulting your doctor. If you stop suddenly, you may have withdrawal symptoms, even though this drug does not seem to be habit-forming. Your doctor will have you taper off gradually.

The safety and effectiveness of Effexor have not been established in children under 18 years of age.

Possible food and drug interactions when taking Effexor XR

Combining Effexor with MAO inhibitors could cause a fatal reaction. (See "Most important fact about this drug.")

Although Effexor does not interact with alcohol, the manufacturer recommends avoiding alcohol while taking this medication.

If you have high blood pressure or liver disease, or are elderly, check with your doctor before combining Effexor with cimetidine (Tagamet).

Effexor does not interact with Lithium or Valium. However, you should consult your doctor before combining Effexor with other drugs that affect the central nervous system, including narcotic painkillers, sleep aids, tranquilizers, antipsychotic medicines such as Haldol, and other antidepressants such as Tofranil.

Effexor has been found to reduce blood levels of the HIV drug Crixivan. It's best to check with your doctor before combining Effexor with any other drug or herbal product.

Special information if you are pregnant or breastfeeding

The effects of Effexor during pregnancy have not been adequately studied. If you are pregnant or are planning to become pregnant, tell your doctor immediately. Effexor should be used during pregnancy only if clearly needed.

If Effexor is taken shortly before delivery, the baby may suffer withdrawal symptoms. It's also known that Effexor appears in breast milk and could cause serious side effects in a nursing infant. You'll need to choose between nursing your baby or continuing your treatment with Effexor.

Recommended dosage of Effexor XR

EFFEXOR

The usual starting dose is 75 milligrams a day, divided into 2 or 3 smaller doses, and taken with food. If needed, your doctor may gradually increase your daily dose in steps of no more than 75 milligrams at a time up to a maximum of 375 milligrams per day.

If you have kidney or liver disease or are taking other medications, your doctor will adjust your dosage accordingly.

EFFEXOR XR

For both depression and anxiety the usual starting dose is 75 milligrams once daily, although some people begin with a dose of 37.5 milligrams for the first 4 to 7 days. Your doctor may gradually increase the dose, in steps of no more than 75 milligrams, up to a maximum of 225 milligrams daily. As with regular Effexor, the doctor will make adjustments in your dosage if you have kidney or liver disease.

Overdosage of Effexor XR

An overdose of Effexor, combined with other drugs or alcohol, can be fatal. If you suspect an overdose, seek medical attention immediately.

• Symptoms of Effexor overdose include: Sleepiness, vertigo, rapid or slow heartbeat, low blood pressure, seizures, coma

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Effexor (venlafaxin) XR Full Prescribing Information

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Find out why Depakene is prescribed, side effects of Depakene, Depakene warnings, effects of Depakene during pregnancy, more - in plain English.

Generic name: Valproic acid
Brand name: Depakene

Pronounced: DEP-uh-keen

Depakene (valproic acid) Full Prescription Information

Why is Depakene prescribed?

Depakene, an epilepsy medicine, is used to treat certain types of seizures and convulsions. It may be prescribed alone or with other anticonvulsant medications.

Most important fact about Depakene

Depakene can cause serious, even fatal, liver damage, especially during the first 6 months of treatment. Children under 2 years of age are the most vulnerable, especially if they are also taking other anticonvulsant medicines and have certain other disorders such as mental retardation. The risk of liver damage decreases with age; but you should always be alert for the following symptoms: loss of seizure control, weakness, dizziness, drowsiness, a general feeling of ill health, facial swelling, loss of appetite, vomiting, and yellowing of the skin and eyes. If you suspect a liver problem, call your doctor immediately.

Note too that Depakene has been known to cause rare cases of life-threatening damage to the pancreas. This problem can develop at any time, even after years of treatment. Call your doctor immediately if any of the following warning signs appear: abdominal pain, loss of appetite, nausea, and vomiting.

How should you take Depakene?

If Depakene irritates your digestive system, take it with food. To avoid irritating your mouth and throat, swallow Depakene capsules whole; do not chew them.

--If you miss a dose...

If you take 1 dose a day, take the dose you missed as soon as you remember. If you do not remember until the next day, skip the dose you missed and go back to your regular schedule.

If you take more than 1 dose a day and you remember the missed dose within 6 hours of the scheduled time, take it immediately. Take the rest of the doses for that day at equally spaced intervals. Never take 2 doses at once.

 

--Storage instructions...

Store at room temperature.

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What side effects may occur using Depakene?

Side effects are more likely if you are taking more than one epilepsy medication, and when you are taking higher doses of Depakene. Indigestion, nausea, and vomiting are the most common side effects when you first start taking this drug.

If any side effects develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Depakene.

• More common side effects of Depakene may include: Abdominal cramps, amnesia, breathing difficulty, depression, diarrhea, dimmed or blurred vision, drowsiness, hair loss, indigestion, infection, involuntary eye movements, loss or increase in appetite, nausea, nervousness, ringing in the ears, sleeplessness, swelling of the arms and legs due to fluid retention, throat inflammation, tremors, vomiting

• Less common or rare side effects may include: Abnormal dreams, abnormal gait, abnormal taste, aggression, anemia, anxiety, back pain, belching, bleeding, blood disorders, bone pain, breast enlargement, breast milk not associated with pregnancy or nursing, bruising, changes in behavior, chest pain, coma, confusion, constipation, cough, deafness, difficulty in speaking, dizziness, double vision, dry skin, dulled senses, ear pain and inflammation, emotional upset, excessive urination (mainly children), feeling of unwellness, fever, gas, growth failure in children, hallucinations, headache, high blood pressure, involuntary jerking, irregular heartbeat, irregular menstrual periods, itching, joint pain, lack of coordination, leg cramps, liver disease, loss of bladder control, loss of coordination, menstrual abnormalities, muscle pain, muscle weakness, nosebleed, overactivity, personality disorder, pneumonia, prickling or tingling sensation, rash, rickets (mainly children), sedation, sensitivity to light, sinus inflammation, skin eruptions or peeling, spots before the eyes, swollen glands, twitching, urinary tract infection, vaginal infection, vertigo, vomiting blood, weakness, weight loss or gain

Why should Depakene not be prescribed?

You should not take this drug if you have liver disease or your liver is not functioning properly, or if you have had an allergic reaction to it.

Special warnings about Depakene

Remember that liver failure is possible when taking Depakene (see "Most important fact about this drug"). Your doctor should test your liver function at regular intervals.

Also keep in mind the threat of damage to the pancreas (see "Most important fact about this drug"). This problem can develop rapidly, so contact your doctor immediately if you experience any symptoms.

In people with a rare set of genetic abnormalities called urea cycle disorders, Depakote may adversely effect the brain. Signs of a developing problem include lack of energy, repeated attacks of vomiting, and mental changes. If you suspect a problem, see your doctor immediately. Depakote may have to be discontinued.

Depakene has also been known to cause a very rare but potentially fatal skin condition. Contact your doctor if you notice any changes in your skin.

Some side effects are more likely if you have manic episodes or suffer from migraines. Your doctor will monitor your care closely if you have one of these conditions.

Because of the potential for side effects involving blood disorders, your doctor will probably test your blood before prescribing Depakene and at regular intervals while you are taking it. Bruising, hemorrhaging, or clotting disorders usually mean the dosage should be reduced or the drug should be stopped altogether.

Depakene may cause drowsiness, especially in older adults. You should not drive a car, operate heavy machinery, or engage in hazardous activity until you know how you react to the drug.

Do not abruptly stop taking this medicine without first consulting your doctor. A gradual reduction in dosage is usually required to prevent major seizures.

This drug can also increase the effect of painkillers and anesthetics. Before any surgery or dental procedure, make sure the doctor knows you are taking Depakene.

Possible food and drug interactions when taking Depakene

If Depakene is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Depakene with the following:

Amitriptyline (Elavil)
Aspirin
Barbiturates such as phenobarbital and Seconal
Blood-thinning drugs such as Coumadin and Dicumarol
Carbamazepine (Tegretol)
Clonazepam (Klonopin)
Diazepam (Valium)
Ethosuximide
Felbamate (Felbatol)
Lamotrigine (Lamictal)
Nortriptyline (Pamelor)
Phenytoin (Dilantin)
Primidone (Mysoline)
Rifampin (Rifater)
Tolbutamide (Orinase)
Zidovudine (Retrovir)

Extreme drowsiness and other serious effects may occur if Depakene is taken with alcohol or other central nervous system depressants such as Halcion, Restoril, or Xanax.

Special information if you are pregnant or breastfeeding

Depakene taken during pregnancy may harm the baby. The drug is not recommended for pregnant women unless the benefits of therapy clearly outweigh the risks. In fact, women in their childbearing years should take Depakene only if it has been shown to be essential in the control of seizures. Since Depakene appears in breast milk, nursing mothers should use it only with caution.

Recommended dosage for Depakene

ADULTS AND CHILDREN 10 OR OLDER

The usual starting dose is 10 to 15 milligrams per 2.2 pounds of body weight per day. Your doctor may increase the dose at weekly intervals by 5 to 10 milligrams per 2.2 pounds per day until seizures are controlled or side effects become too severe. If stomach upset develops, the dose may be increased more slowly. The daily dose should not exceed 60 milligrams per 2.2 pounds per day.

OLDER ADULTS

Older adults generally are prescribed reduced starting doses, and receive dosage increases more gradually than younger people.

Overdosage of Depakene

Any medication taken in excess can have serious consequences. An overdose of Depakene can be fatal. If you suspect an overdose, seek medical help immediately.

• Symptoms of Depakene overdose may include: Coma, extreme drowsiness, heart problems

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Depakene (valproic acid) Full Prescription Information

Detailed Info on Signs, Symptoms, Causes, Treatments of Bipolar Disorder

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Find out why trihexyphenidyl is prescribed, side effects of trihexyphenidyl, trihexyphenidyl warnings, effects of trihexyphenidyl during pregnancy, more - in plain English.

Generic name: Trihexyphenidyl hydrochloride

Trihexyphenidyl Full Prescribing Information

Why is Trihexyphenidyl prescribed?

Trihexyphenidyl is used, in conjunction with other drugs, for the relief of certain symptoms of Parkinson's disease, a brain disorder that causes muscle tremor, stiffness, and weakness. It is also used to control certain side effects induced by antipsychotic drugs such as Thorazine and Haldol. Trihexyphenidyl works by correcting the chemical imbalance that causes Parkinson's disease.

Most important fact about Trihexyphenidyl

Trihexyphenidyl is not a cure for Parkinson's disease; it merely minimizes and reduces the frequency of symptoms such as tremors.

How should you take Trihexyphenidyl?

You may take Trihexyphenidyl either before meals or after meals, whichever you find more convenient. Your doctor will probably start you on a small amount and increase the dosage gradually. Take Trihexyphenidyl exactly as prescribed.

If the medication makes your mouth feel dry, try chewing gum, sucking mints, or simply sipping water.

Trihexyphenidyl comes in tablet and liquid form. With either, you will probably need to take 3 or 4 doses a day.

Once you have reached the dosage that is best for you, your doctor may switch you to sustained-release capsules ("Sequels") which are to be taken only once or twice a day. Do not open or crush the sequels. Always swallow them whole.

--If you miss a dose...

Take it as soon as you remember. If it is within 2 hours or your next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at the same time.

--Storage instructions...

Store at room temperature. Do not allow the liquid to freeze.

What side effects may occur taking trihexyphenidyl?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Trihexyphenidyl.

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• Common side effects of Trihexyphenidyl​​​​​​​ may include: Blurred vision, dry mouth, nausea, nervousness

These side effects, which appear in 30% to 50% of all people who take Trihexyphenidyl, tend to be mild. They may disappear as your body gets used to the drug; if they persist, your doctor may want to lower your dosage slightly.

• Other potential side effects include: Agitation, bowel obstruction, confusion, constipation, delusions, difficulty urinating, dilated pupils, disturbed behavior, drowsiness, hallucinations, headache, pressure in the eye, rapid heartbeat, rash, vomiting, weakness

Why should Trihexyphenidyl not be prescribed?

Do not take Trihexyphenidyl if you are known to be sensitive to it or if you have ever had an allergic reaction to it or to other antiparkinson medications of this type.

Special warnings about Trihexyphenidyl 

The elderly are highly sensitive to drugs such as Trihexyphenidyl and should use it with caution.

Artane can reduce the body's ability to perspire, one of the key ways your body prevents overheating. Avoid excess sun or exercise that also cause you to become overheated.

If you have any of the following conditions, make sure your doctor knows about them, since Trihexyphenidyl could make them worse:

Enlarged prostate
Glaucoma
Stomach/intestinal obstructive disease
Urinary tract obstructive disease

It is important to stick to the prescribed dosage; taking larger amounts "for kicks" could lead to an overdose.

Your doctor should watch you carefully if you have heart, liver, or kidney disease or high blood pressure, and should check your eyes frequently. You should also be watched for the development of any allergic reactions.

Possible food and drug interactions when taking Trihexyphenidyl

If you take Trihexyphenidyl along with any of the drugs listed below, your doctor may need to adjust the dosage of Trihexyphenidyl, the other medication, or possibly both.

Amantadine (Symmetrel)
Amitriptyline (Elavil)
Chlorpromazine (Thorazine)
Doxepin (Sinequan)
Haloperidol (Haldol)

Special information if you are pregnant or breastfeeding

No specific information is available concerning the use of Artane during pregnancy or breastfeeding. If you are pregnant or plan to become pregnant while taking Artane, inform your doctor immediately.

Recommended dosage for Trihexyphenidyl

Your doctor will individualize the dose to your needs, starting with a low dose and then increasing it gradually, especially if you are over 60 years of age.

ADULTS

Parkinson's Disease:

The usual starting dose, in tablet or liquid form, is 1 milligram on the first day.

After the first day, your doctor may increase the dose by 2 milligrams at intervals of 3 to 5 days, until you are taking a total of 6 to 10 milligrams a day.

Your total daily dose will depend upon what is found to be the most effective level. For many people, 6 to 10 milligrams is most effective. Some, however, may require a total daily dose of 12 to 15 milligrams.

Drug-Induced Parkinsonism:

Your doctor will have to determine by trial and error the size and frequency of the dose of Trihexyphenidyl needed to control the tremors and muscle rigidity that sometimes result from commonly used tranquilizers.

The total daily dosage usually ranges between 5 and 15 milligrams, although, in some cases, symptoms have been satisfactorily controlled on as little as 1 milligram daily.

Your doctor may start you on 1 milligram of Trihexyphenidyl a day. If your symptoms are not controlled in a few hours, he or she may slowly increase the dose until satisfactory control is achieved.

Use of Trihexyphenidyl​​​​​​​ with Levodopa:

When Trihexyphenidyl is used at the same time as levodopa, the usual dose of each may need to be reduced. Your doctor will adjust the dosages carefully, depending on the side effects and the degree of symptom control. Trihexyphenidyl dosage of 3 to 6 milligrams daily, divided into equal doses, is usually adequate.

Trihexyphenidyl​​​​​​​ tablets and Liquid:

You will be able to handle the total daily intake of Trihexyphenidyl tablets or liquid best if the medication is divided into 3 doses and taken at mealtimes. If you are taking high doses (more than 10 milligrams daily), your doctor may divide them into 4 parts, so that you take 3 doses at mealtimes and the fourth at bedtime.

Overdosage of Trihexyphenidyl

Overdosage with Artane may cause agitation, delirium, disorientation, hallucinations, or psychotic episodes.

• Other symptoms may include: Clumsiness or unsteadiness, fast heartbeat, flushing of skin, seizures, severe drowsiness, shortness of breath or troubled breathing, trouble sleeping, unusual warmth

If you suspect an overdose of Trihexyphenidyl, seek medical attention immediately.

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Trihexyphenidyl Full Prescribing Information

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Find out why Stelazine is prescribed, side effects of Stelazine, Stelazine warnings, effects of Stelazine during pregnancy, more - in plain English.

Generic name: Trifluoperazine hydrochloride
Brand name: Stelazine

Pronounced: STEL-ah-zeen

Full Stelazine Prescribing Information

Why is Stelazine prescribed?

Stelazine is used for the treatment of schizophrenia (severe disruptions in thought and perception). It is also prescribed for anxiety that does not respond to ordinary tranquilizers.

Most important fact about Stelazine

Stelazine may cause tardive dyskinesia--a condition marked by involuntary muscle spasms and twitches in the face and body. This condition may be permanent and appears to be most common among the elderly, especially women. Ask your doctor for information about this possible risk.

How should you take Stelazine?

If taking Stelazine in a liquid concentrate form, you will need to dilute it with a liquid such as a carbonated beverage, coffee, fruit juice, milk, tea, tomato juice, or water. You can also use puddings, soups, and other semisolid foods. Stelazine should be diluted just before you take it.

You should not take Stelazine with alcohol.

--If you miss a dose...

Why is Stelazine prescribed?

Stelazine is used for the treatment of schizophrenia (severe disruptions in thought and perception). It is also prescribed for anxiety that does not respond to ordinary tranquilizers.

Most important fact about Stelazine

Stelazine may cause tardive dyskinesia--a condition marked by involuntary muscle spasms and twitches in the face and body. This condition may be permanent and appears to be most common among the elderly, especially women. Ask your doctor for information about this possible risk.

How should you take Stelazine?

 

If taking Stelazine in a liquid concentrate form, you will need to dilute it with a liquid such as a carbonated beverage, coffee, fruit juice, milk, tea, tomato juice, or water. You can also use puddings, soups, and other semisolid foods. Stelazine should be diluted just before you take it.

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You should not take Stelazine with alcohol.

--If you miss a dose...

If you take 1 dose a day, take the dose you missed as soon as you remember. Then go back to your regular schedule. If you do not remember until the next day, skip the missed dose and go back to your regular schedule.

If you take more than 1 dose a day, take the dose you missed if it is within an hour or so of the scheduled time. If you do not remember until later, skip the missed dose and go back to your regular schedule. Do not take 2 doses at once.

--Storage instructions...

Store at room temperature. Protect the concentrate from light.

What side effects may occur with taking Stelazine?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Stelazine.

• Side effects of Stelazine may include: Abnormal secretion of milk, abnormal sugar in urine, abnormalities in movement and posture, agitation, allergic reactions (sometimes severe), anemia, asthma, blood disorders, blurred vision, body rigidly arched backward, breast development in males, chewing movements, constipation, constricted pupils, difficulty swallowing, dilated pupils, dizziness, drooling, drowsiness, dry mouth, ejaculation problems, exaggerated or excessive reflexes, excessive or spontaneous flow of milk, eye problems causing a state of fixed gaze, eye spasms, fatigue, fever or high fever, flu-like symptoms, fluid accumulation and swelling (including the brain), fragmented movements, headache, heart attack, high or low blood sugar, hives, impotence, inability to urinate, increase in appetite and weight, infections, insomnia, intestinal blockage, involuntary movements of tongue, face, mouth, jaw, arms, and legs, irregular blood pressure, pulse, and heartbeat, irregular or no menstrual periods, jitteriness, light-headedness (especially when standing up), liver damage, lockjaw, loss of appetite, low blood pressure, mask-like face, muscle stiffness and rigidity, nasal congestion, nausea, persistent, painful erections, pill-rolling movement, protruding tongue, puckering of mouth, puffing of cheeks, purple or red spots on the skin, rapid heartbeat, restlessness, rigid arms, feet, head, and muscles, seizures, sensitivity to light, shuffling walk, skin inflammation and peeling, skin itching, pigmentation, reddening, or rash, spasms in jaw, face, tongue, neck, hands, feet, back, and mouth, sweating, swelling of the throat, totally unresponsive state, tremors, twisted neck, weakness, yellowing of skin and whites of eyes

Why should Stelazine not be prescribed?

You should not be using Stelazine if you have liver damage, or if you are taking central nervous system depressants such as alcohol, barbiturates, or narcotic pain relievers. Stelazine should not be used if you have an abnormal bone marrow or blood condition.

Special warnings about Stelazine

You should use Stelazine cautiously if you have ever had a brain tumor, breast cancer, intestinal blockage, the eye condition called glaucoma, heart or liver disease, or seizures. Be cautious, too, if you are exposed to certain pesticides or extreme heat. Be aware that Stelazine may hide the signs of overdose of other drugs and may make it more difficult for your doctor to diagnose intestinal obstruction, brain tumor, and the dangerous neurological condition called Reye's syndrome.

Tell your doctor if you have ever had an allergic reaction to any major tranquilizer similar to Stelazine.

Dizziness, nausea, vomiting, and tremors can result if you suddenly stop taking Stelazine. Follow your doctor's instructions when discontinuing this drug.

Tell your doctor immediately if you experience symptoms such as a fever or sore throat, mouth, or gums. These signs of infection may signal the need to stop Stelazine treatment. Notify your doctor, too, if you develop flu-like symptoms with fever.

This drug may impair your ability to drive a car or operate potentially dangerous machinery, especially during the first few days of treatment. Do not participate in any activities that require full alertness if you are unsure about your ability.

If you have any trouble with your vision, tell your doctor.

Stelazine concentrate contains a sulfite that may cause allergic reactions in some people, especially in those with asthma.

Stelazine can cause a group of symptoms called Neuroleptic Malignant Syndrome. Signs are high body temperature, rigid muscles, irregular pulse or blood pressure, rapid or abnormal heartbeat, and excessive perspiration.

Possible food and drug interactions when taking Stelazine

Extreme drowsiness and other potentially serious effects can result if Stelazine is combined with alcohol, tranquilizers such as Valium, narcotic painkillers such as Percocet, antihistamines such as Benadryl, and barbiturates such as phenobarbital.

If Stelazine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Stelazine with the following:

Antiseizure drugs such as Dilantin
Atropine (Donnatal)
Blood thinners such as Coumadin
Guanethidine
Lithium (Lithobid, Eskalith)
Propranolol (Inderal)
Thiazide diuretics such as Dyazide

Special information if you are pregnant or breastfeeding

Pregnant women should use Stelazine only if clearly needed. The effects of Stelazine during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Stelazine appears in breast milk and may affect a nursing infant. If this medication is essential to your health, your doctor may have you discontinue breastfeeding while you are taking it.

Recommended dosage for Stelazine

ADULTS

Nonpsychotic Anxiety

Doses usually range from 2 to 4 milligrams daily. This amount should be divided into 2 equal doses and taken twice a day. Do not take more than 6 milligrams a day or take the medication for more than 12 weeks.

Schizophrenia

The usual starting dose is 4 to 10 milligrams a day, divided into 2 equal doses; doses range from 15 to 40 milligrams daily.

CHILDREN

Doses are based on the child's weight and the severity of his or her symptoms.

Schizophrenia in Children 6 to 12 Years Old Who Are Closely Monitored or Hospitalized

The starting dose is 1 milligram a day, taken all at once or divided into 2 doses. Your doctor will increase the dosage gradually, up to 15 milligrams a day.

OLDER ADULTS

Older people usually take Stelazine at lower doses. Because you may develop low blood pressure while taking this drug, your doctor will watch you closely. Older people (especially older women) may be more susceptible to tardive dyskinesia--a possibly permanent condition characterized by involuntary muscle spasms and twitches in the face and body. Consult your doctor for information about these potential risks.

Overdosage of Stelazine

Any medication taken in excess can have serious consequences. If you suspect an overdose of Stelazine, seek medical help immediately.

• Symptoms of Stelazine overdose may include: Agitation, coma, convulsions, difficulty breathing, difficulty swallowing, dry mouth, extreme sleepiness, fever, intestinal blockage, irregular heart rate, low blood pressure, restlessness

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Full Stelazine Prescribing Information

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Generic Name: protriptyline
Brand Names: Vivactil, Triptil

Vivactil (protriptyline) Full Prescribing Information

Vivactil (protriptyline) Medication Guide

What is Vivactil (protriptyline)?

Protriptyline is in a group of drugs called tricyclic antidepressants. Protriptyline affects chemicals in the brain that may become unbalanced.

Protriptyline is used to treat symptoms of depression.

Protriptyline may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Vivactil (protriptyline)?

Do not use protriptyline if you have recently had a heart attack, or if you have taken cisapride (Propulsid) or used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.
You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself

What should I discuss with my healthcare provider before taking Vivactil (protriptyline)?

 

Do not use this medication if you are allergic to protriptyline, or if you have recently had a heart attack. Do not use protriptyline if you have taken cisapride (Propulsid) or used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take protriptyline before the MAO inhibitor has cleared from your body. Before taking protriptyline, tell your doctor if you are allergic to any drugs, or if you have:

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• heart disease;
• a history of heart attack, stroke, or seizures;
• bipolar disorder (manic-depression);
• schizophrenia or other mental illness;
• diabetes (protriptyline may raise or lower blood sugar);
• glaucoma; or
• problems with urination.

If you have any of these conditions, you may not be able to use protriptyline, or you may need a dosage adjustment or special tests during treatment.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether protriptyline passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not give this medication to anyone under 18 years old without the advice of a doctor.

How should I take Vivactil (protriptyline)?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Follow the directions on your prescription label.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking protriptyline. You may need to stop using the medicine for a short time.

Do not stop using protriptyline without first talking to your doctor. You may need to use less and less before you stop the medication completely. Stopping this medication suddenly could cause you to have unpleasant side effects. It may take a few weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve during treatment with protriptyline. Store protriptyline at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

 

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of protriptyline can be fatal. Symptoms of a protriptyline overdose may include extreme drowsiness, confusion, agitation, hallucinations, blurred vision, muscle stiffness, feeling hot or cold, seizure (convulsions), or coma.

What should I avoid while taking Vivactil (protriptyline)?

Avoid drinking alcohol. It can cause dangerous side effects when taken together with protriptyline.

Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, medicine for seizures, or other antidepressants). They can add to sleepiness caused by protriptyline.

Grapefruit and grapefruit juice may interact with protriptyline. Discuss the use of grapefruit products with your doctor before increasing or decreasing the amount of grapefruit products in your diet.

Protriptyline can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Protriptyline can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Vivactil (protriptyline) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

• fast, pounding, or uneven heart rate;
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance;
• confusion, hallucinations, or seizure (convulsions);
• easy bruising or bleeding, unusual weakness;
• restless muscle movements in your eyes, tongue, jaw, or neck;
• urinating less than usual or not at all;
• extreme thirst with headache, nausea, vomiting, and weakness; or
• feeling light-headed or fainting.

Less serious side effects may be more likely to occur, such as:

• nausea, vomiting, stomach pain, loss of appetite;
• constipation or diarrhea;
• dry mouth, unpleasant taste;
• weakness, lack of coordination;
• feeling anxious, restless, dizzy, drowsy, or tired;
• sleep problems (insomnia), nightmares;
• blurred vision, headache, ringing in your ears;
• breast swelling (in men or women); or
• decreased sex drive, impotence, or difficulty having an orgasm.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect Vivactil (protriptyline)?

Before taking protriptyline, tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft).

Before taking protriptyline, tell your doctor if you are currently using any of the following drugs:

• cimetidine (Tagamet);
• guanethidine (Ismelin);
• tramadol (Ultram);
• heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), or quinidine (Cardioquin, Quinidex, Quinaglute); or
• anti-psychotic medications such as chlorpromazine (Thorazine), haloperidol (Haldol), thioridazine (Mellaril), clozapine (Clozaril), olanzapine (Zyprexa, Zydis), quetiapine (Seroquel), risperidone (Risperdal), ziprasidone (Geodon), and others.

If you are using any of these drugs, you may not be able to use protriptyline, or you may need dosage adjustments or special tests during treatment.

There are many other medicines that can interact with protriptyline. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

• Your pharmacist has information about protriptyline written for health professionals that you may read.

What does my medication look like?

Protriptyline is available with a prescription under the brand name Vivactil. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication especially if it is new to you.

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Last revision: 05/22/2007

Vivactil (protriptyline) Full Prescribing Information

Vivactil (protriptyline) Medication Guide

Detailed Info on Signs, Symptoms, Causes, Treatments of Depression

back to: Psychiatric Medication Patient Information Index

Chapter 103 of the book Self-Help Stuff That Works

by Adam Khan

IF YOU FEEL LIKE YAWNING before you finish this article, go right ahead. You know how satisfying a good yawn can be.

I've just given you a suggestion, and whether you like it or not, it has had an effect on you. Just by suggesting something, you can have an influence on people. You don't have to boss them around or be sly to have an influence. You can merely suggest, which is easier and creates less strain on yourself and other people - less strain than either trying to command or trying to be clever.

Of course, if you're a manager or a parent, you'll have to do your share of commanding. But much of what we want other people to do is not in the "must do" category. Most of it is simply our preference. And changing people to fit our preferences is best done with simple suggestions.

We continually influence one another. Hypnosis practitioners find that we are in a semihypnotic state most of the time - our focus is limited and we are open to suggestion. If this is true, and it seems to be so, you can deliberately make the world around you better by speaking up. Say what you think. Suggest things.

You don't have to be pushy, pompous or sneaky. Just be your honest self. And while not all of your suggestions will have an effect, a surprising number of them will, often without your knowledge or even the knowledge of the other. Sometimes you will find people doing what you suggested but they have forgotten it was your suggestion - they think it was their idea. Whether you get the credit or not, whether some of your suggestions are ignored or not, one thing is certain: You'll get more of what you prefer when you speak up than you will by keeping silent, as long as you speak up in a way that doesn't create resistance.

Suggest something. Give yourself permission to have an effect on people. I know you've got some good ideas in that head of yours. I think you should let them out. But it's only a suggestion.

Influence people by merely suggesting things.

How to be here now. This is mindfulness from the East applied to reality in the West.
E-Squared

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Expressing anger has a good reputation. Too bad. Anger is one of the most destructive emotions we experience, and its expression is dangerous to our relationships.
Danger

It is unnecessarily limiting to label yourself shy, outgoing, Aries, Taurus, strong, weak, or any other label. Be your true, flexible self and you'll be better off.
Personality Myth

There may be evidence that prayer may actually have medical benefits, even if the prayed-for doesn't know it's happening.
Send a Blessing

next: We're Family

What is trimipramine?

Trimipramine is in a group of drugs called tricyclic antidepressants. Trimipramine affects chemicals in the brain that may become unbalanced.

Trimipramine is used to treat symptoms of depression.

Trimipramine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about trimipramine?

Do not use this medication if you are allergic to trimipramine, or if you have recently had a heart attack. Do not use trimipramine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days.
You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

What should I discuss with my healthcare provider before taking trimipramine?

Do not use this medication if you are allergic to trimipramine, or if you have recently had a heart attack. Do not use trimipramine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take trimipramine before the MAO inhibitor has cleared from your body.
Before taking trimipramine, tell your doctor if you are allergic to any drugs, or if you have:

• heart disease;
• a history of heart attack, stroke, or seizures;
• bipolar disorder (manic-depression);
• schizophrenia or other mental illness;
• kidney disease;
• overactive thyroid;
• diabetes (trimipramine may raise or lower blood sugar);
• glaucoma; or
• problems with urination.

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If you have any of these conditions, you may not be able to use trimipramine, or you may need a dosage adjustment or special tests during treatment.

 

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

FDA Pregnancy Category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Trimipramine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Older adults may be more likely to have side effects from this medication.

Do not give this medication to anyone under 18 years old without the advice of a doctor.

How should I take trimipramine?

Take this medication exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Your doctor may occasionally change your dose to make sure you get the best results from this medication. Follow the directions on your prescription label.

If you need to have any type of surgery, tell the surgeon ahead of time that you are taking trimipramine. You may need to stop using the medicine for a short time.

Do not stop using trimipramine without first talking to your doctor. You may need to use less and less before you stop the medication completely. Stopping this medication suddenly could cause you to have unpleasant side effects. It may take up to 4 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve after 4 weeks of treatment. Do not use this medication for longer than 3 months unless your doctor has told you to. Store trimipramine at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of trimipramine can be fatal.
Symptoms of a trimipramine overdose may include uneven heartbeats, extreme drowsiness, agitation, vomiting, blurred vision, confusion, hallucinations, muscle stiffness, feeling light-headed, fainting, seizure (convulsions), or coma.

What should I avoid while taking trimipramine?

Avoid drinking alcohol. It can cause dangerous side effects when taken together with trimipramine.
Avoid using other medicines that make you sleepy (such as cold medicine, pain medication, muscle relaxers, medicine for seizures, or other antidepressants). They can add to sleepiness caused by trimipramine.

Grapefruit and grapefruit juice may interact with trimipramine. Discuss the use of grapefruit products with your doctor before increasing or decreasing the amount of grapefruit products in your diet.

Trimipramine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid exposure to sunlight or artificial UV rays (sunlamps or tanning beds). Trimipramine can make your skin more sensitive to sunlight and sunburn may result. Use a sunscreen (minimum SPF 15) and wear protective clothing if you must be out in the sun.

Trimipramine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any new or worsening symptoms such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have any of these serious side effects:

• fast, pounding, or uneven heart rate;
• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;
• sudden numbness or weakness, especially on one side of the body;
• sudden headache, confusion, problems with vision, speech, or balance;
• confusion, hallucinations, or seizure (convulsions);
• easy bruising or bleeding, unusual weakness;
• feeling light-headed, fainting;
• restless muscle movements in your eyes, tongue, jaw, or neck;
• urinating more or less than usual;
• extreme thirst with headache, nausea, vomiting, and weakness; or
• skin rash, bruising, severe tingling, numbness, pain, and muscle weakness.

Less serious side effects may be more likely to occur, such as:

• nausea, vomiting, stomach pain, loss of appetite;
• constipation or diarrhea;
• dry mouth, unpleasant taste;
• weakness, lack of coordination;
• numbness or tingly feeling;
• feeling dizzy, or drowsy;
• blurred vision, headache, ringing in your ears;
• mild skin rash;
• low fever;
• breast swelling (in men or women); or
• decreased sex drive, impotence, or difficulty having an orgasm.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

What other drugs will affect trimipramine?

Before taking trimipramine, tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft).

Before taking trimipramine, tell your doctor if you are currently using any of the following drugs:

• cimetidine (Tagamet);
• guanethidine (Ismelin); or
• heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), or quinidine (Cardioquin, Quinidex, Quinaglute).

If you are using any of these drugs, you may not be able to use trimipramine, or you may need dosage adjustments or special tests during treatment.

There are many other medicines that can interact with trimipramine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.

Where can I get more information?

• Your pharmacist has information about trimipramine written for health professionals that you may read.

What does my medication look like?

Trtrimipramine is available with a prescription under the brand name Surmontil. Other brand or generic formulations may also be available. Ask your pharmacist any questions you have about this medication, especially if it is new to you.

• Surmontil 25 mg-blue/yellow capsules
• Surmontil 50 mg-blue/orange capsules
• Surmontil 100 mg-blue/white capsules

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Last revision: 05/22/2007

Surmontil (Trimipramine) full prescribing information

Detailed Info on Signs, Symptoms, Causes, Treatments of Depression

back to: Psychiatric Medication Patient Information Index

Find out why Halcion is prescribed, side effects of Halcion, Halcion warnings, effects of Halcion during pregnancy, more - in plain English.

Generic name: Triazolam
Brand name: Halcion

Pronounced: HAL-see-on

Full Halcion (Triazolam) Prescription Information

Why is Halcion prescribed?

Halcion is used for short-term treatment of insomnia. It is a member of the benzodiazepine class of drugs, many of which are used as tranquilizers.

Most important fact about Halcion

Sleep problems are usually temporary, requiring treatment for only a short time, usually 1 or 2 days and no more than 1 to 2 weeks. Insomnia that lasts longer than this may be a sign of another medical problem. If you find you need this medicine for more than 7 to 10 days, be sure to check with your doctor.

How should you take Halcion?

Take this medication exactly as directed; never take more than your doctor has prescribed.

---If you miss a dose...

Take Halcion only as needed.

---Storage instructions...

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature.

What side effects may occur using Halcion?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Halcion.

• More common side effects of Halcion may include: Coordination problems, dizziness, drowsiness, headache, light-headedness, nausea/vomiting, nervousness

• Less common or rare side effects may include: Aggressiveness, agitation, behavior problems, burning tongue, changes in sexual drive, chest pain, confusion, congestion, constipation, cramps/pain, delusions, depression, diarrhea, disorientation, dreaming abnormalities, drowsiness, dry mouth, exaggerated sense of well-being, excitement, fainting, falling, fatigue, hallucinations, impaired urination, inappropriate behavior, incontinence, inflammation of the tongue and mouth, irritability, itching, loss of appetite, loss of sense of reality, memory impairment, memory loss (e.g. traveler's amnesia), menstrual irregularities, morning "hangover" effects, muscle spasms in the shoulders or neck, nightmares, rapid heart rate, restlessness, ringing in the ears, skin inflammation, sleep disturbances including insomnia, sleepwalking, slurred or difficult speech, stiff awkward movements, taste changes, tingling or pins and needles, tiredness, visual disturbances, weakness, yellowing of the skin and whites of the eyes

   

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Why should Halcion not be prescribed?

You should not take this drug if you are pregnant or if you have had an allergic reaction to it or to other benzodiazepine drugs such as Valium.

Also avoid Halcion if you are taking the antifungal medications Nizoral or Sporanox, or the antidepressant Serzone.

Special warnings about Halcion

When Halcion is used every night for more than a few weeks, it loses its effectiveness to help you sleep. This is known as tolerance. Also, it can cause dependence, especially when it is used regularly for longer than a few weeks or at high doses.

Abrupt discontinuation of Halcion should be avoided, since it has been associated with withdrawal symptoms (convulsions, cramps, tremor, vomiting, sweating, feeling ill, perceptual problems, and insomnia). A gradual dosage tapering schedule is usually recommended for patients taking more than the lowest dose of Halcion for longer than a few weeks. The usual treatment period is 7 to 10 days.

If you develop unusual and disturbing thoughts or behavior---including increased anxiety or depression---during treatment with Halcion, you should discuss them with your doctor immediately.

"Traveler's amnesia" has been reported by patients who took Halcion to induce sleep while traveling. To avoid this condition, do not take Halcion on an overnight airplane flight of less than 7 to 8 hours.

You may suffer increased anxiety during the daytime while taking Halcion.

When you first start taking Halcion, until you know whether the medication will have any "carry over" effect the next day, use extreme care while doing anything that requires complete alertness such as driving a car or operating machinery.

After discontinuing the drug, you may experience a "rebound insomnia" for the first 2 nights---that is, insomnia may be worse than before you took the sleeping pill.

You should be aware that anterograde amnesia (forgetting events after an injury) has been associated with benzodiazepine drugs such as Halcion.

You should be cautious about using this drug if you have liver or kidney problems, lung problems, or a tendency to temporarily stop breathing while you are asleep.

Possible food and drug interactions when taking Halcion

Avoid alcoholic beverages and grapefruit juice.

If Halcion is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Halcion with the following:

Amiodarone (Cordarone)
Antidepressant medications, including "tricyclic" drugs such as Elavil and such MAO inhibitors as Nardil and Parnate
Antihistamines such as Benadryl and Tavist
Barbiturates such as phenobarbital and Seconal
Cimetidine (Tagamet)
Clarithromycin (Biaxin)
Cyclosporine (Sandimmune Neoral)
Diltiazem (Cardizem)
Ergotamine (Cafergot)
Erythromycin (E.E.S., PCE, E-Mycin, others)
Fluvoxamine (Luvox)
Isoniazid (Nydrazid)
Itraconazole (Nizoral)
Ketoconazole (Sporanox)
Narcotic painkillers such as Demerol
Major tranquilizers such as Mellaril and Thorazine
Nefazodone (Serzone)
Nicardipine (Cardene)
Nifedipine (Adalat)
Other tranquilizers such as BuSpar, Valium, and Xanax
Oral contraceptives
Paroxetine (Paxil)
Ranitidine (Zantac)
Seizure medications such as Dilantin and Tegretol
Sertraline (Zoloft)
Verapamil (Calan)

Special information if you are pregnant or breastfeeding

Since benzodiazepines have been associated with damage to the developing baby, you should not take Halcion if you are pregnant, think you may be pregnant, or are planning to become pregnant; or if you are breastfeeding.

Recommended dosage for Halcion

ADULTS

The usual dose is 0.25 milligram before bedtime. The dose should never be more than 0.5 milligram.

CHILDREN

Safety and effectiveness for children under the age of 18 have not been established.

OLDER ADULTS

To decrease the possibility of oversedation, dizziness, or impaired coordination, the usual starting dose is 0.125 milligram. This may be increased to 0.25 milligram if necessary.

Overdosage of Halcion

Any medication taken in excess can have serious consequences. Severe overdosage of Halcion can be fatal. If you suspect an overdose, seek medical help immediately.

• Symptoms of Halcion overdose may include: Apnea (temporary cessation of breathing), coma, confusion, excessive sleepiness, problems in coordination, seizures, shallow or difficult breathing, slurred speech

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Full Halcion (Triazolam) Prescription Information

Extensive information on Anxiety Disorders, signs, symptoms, causes, treatment

back to: Psychiatric Medication Patient Information Index

Chapter 3:

This booklet comprises chosen topics from a wider domain - chosen for their essentially, for the explanation of the practical guidelines offered to the reader, or the concrete steps suggested to him. It belongs to the fast growing "Do It Yourself" library. It's main message is "Feel It Yourself" and it is mainly intended for three types of readers:

The first type consists of those who relate to their emotions as a factor which contributes a great deal to their lives. They regard the feelings of the daily life experience of human existence as a blessing that enriches them - and not as a calamity or pathology. This way of relating to emotions is characteristic to most of the Bohemians and other people active in various fields of the arts. Recently, it has become the main mode of relating for wider circles of society.

Lately, the increase in this mode of relating to emotion is overwhelming, and it is prevalent even among very "sane" people. The main contributing factor to this phenomenon is the very fast growth in the number of those who believe that "life should be a valuable experience that is worth living and not a purpose, mission or punishment".

The second kind of person this booklet is meant for is the increasing number of people who are aware (at least partially) that emotions are not only something that happens to them or to others. These people are from the growing sector of the population who are involved with interpersonal relations to a great extent.

Because of their training and occupation they become progressively more aware that their emotions - as well as those of others - are something that they use (and manipulate) for different purposes. Many of these people feel or think that it would suit them to become more sophisticated users.

The third kind of potential readers are those to whom the topics dwelt on in this booklet seem very familiar. This group of potential readers includes all those who have discovered in a vicarious way or by chance or because of ideas they have picked up somewhere... the curious effects of the willful manipulation of the attention paid to the felt sensations of the body.

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Many of them have found, by themselves, that the concentration of attention on the common headache - if done persistently - tends to weaken it or even cause it to disappear. Some of them generalized from the headaches to the unpleasant sensations of other parts of the body. A small minority even applied this to the more vague and hard-to-place feelings and moods.

This kind of potential reader also includes all those individuals who are used to being "in touch with themselves". For many different reasons, people get into this habit. Having this trend - intentionally or unintentionally - they are used to `listening' to their physical sensations and thus, to all the felt senses of their feelings, emotions, moods, passions, etc.

So:

• If for one reason or another you wish to improve your understanding of the human emotional system and its functioning, and especially if you wish to improve the functioning and quality of your emotional system - this booklet is meant for you.
• If all you want is only to improve the quality of your ongoing feelings and moods or a certain aspect of your life - this book is for you too.
• This book may also be useful to professionals whose work is involved with the emotional systems of others. We hope they will not misuse it.
• The reader who wants to become acquainted with the emotional domain as a whole, before taking steps to change it, is advised to read first the theoretical chapters.
• The reader who is more interested in the practical side of the new technique is advised to start with chapter five entitled "Do it yourself now", which is a guide for training oneself in the use of the focusing technique.
• Readers who work in the domain of the social sciences, are advised to read the following chapter as a summary of the theory and the concepts of my version of the sensate focusing.
• Readers who are interested in topics that are mentioned but not explained in the booklet in detail, are invited to write us about them (or even to phone). They may get a copy of the preliminary drafts dealing with those topics, which, for one reason or another, were not included in this edition.

next: Key to Concepts, Abbreviations and Strange Words

Find out why Desyrel is prescribed, Desyrel side effects, Desyrel warnings, effects of Desyrel during pregnancy, more - in plain English.

Generic name: Trazodone hydrochloride
Brand name: Desyrel

Pronounced: DES-ee-rel

Desyrel (trazodone) Full Prescribing Information

Why is Desyrel prescribed?

Desyrel is prescribed for the treatment of depression.

Most important fact about Desyrel

Desyrel does not provide immediate relief. It may take up to 4 weeks before you begin to feel better, although most patients notice improvement within 2 weeks.

How should you take Desyrel?

Take Desyrel shortly after a meal or light snack. You may be more apt to feel dizzy or light-headed if you take the drug before you have eaten.

Desyrel may cause dry mouth. Sucking on a hard candy, chewing gum, or melting bits of ice in your mouth can relieve the problem.

--If you miss a dose...

Take it as soon as you remember. If it is within 4 hours of your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at once.

--Storage instructions...

Store at room temperature in a tightly closed container away from light and excessive heat.

What side effects may occur with Desyrel?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Desyrel.

• • More common Desyrel side effects may include: Abdominal or stomach disorder, aches or pains in muscles and bones, anger or hostility, blurred vision, brief loss of consciousness, confusion, constipation, decreased appetite, diarrhea, dizziness or light-headedness, drowsiness, dry mouth, excitement, fainting, fast or fluttery heartbeat, fatigue, fluid retention and swelling, headache, inability to fall or stay asleep, low blood pressure, nasal or sinus congestion, nausea, nervousness, nightmares or vivid dreams, tremors, uncoordinated movements, vomiting, weight gain or loss

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• Less common or rare side effects may include: Allergic reactions, anemia, bad taste in mouth, blood in the urine, chest pain, delayed urine flow, decreased concentration, decreased sex drive, disorientation, ejaculation problems, excess salivation, gas, general feeling of illness, hallucinations or delusions, high blood pressure, impaired memory, impaired speech, impotence, increased appetite, increased sex drive, menstrual problems, more frequent urination, muscle twitches, numbness, prolonged erections, red, tired, itchy eyes, restlessness, ringing in the ears, shortness of breath, sweating or clammy skin, tingling or pins and needles

Why should Desyrel not be prescribed?

If you are sensitive to or have ever had an allergic reaction to Desyrel or similar drugs, you should not take this medication. Make sure your doctor is aware of any drug reactions you have experienced.

 

Special warnings about Desyrel

Desyrel may cause you to become drowsy or less alert and may affect your judgment. Therefore, you should not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until you know how this drug affects you.

Desyrel has been associated with priapism, a persistent, painful erection of the penis. Men who experience prolonged or inappropriate erections should stop taking this drug and consult their doctor.

Notify your doctor or dentist that you are taking this drug if you have a medical emergency, and before you have surgery or dental treatment. Your doctor will ask you to stop using the drug if you are going to have elective surgery.

Be careful taking this drug if you have heart disease. Desyrel can cause irregular heartbeats.

Possible food and drug interactions when taking Desyrel

Desyrel may intensify the effects of alcohol. Do not drink alcohol while taking this medication.

If Desyrel is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Desyrel with the following:

Antidepressant drugs known as MAO inhibitors, including Nardil and Parnate
Barbiturates such as Seconal
Central nervous system depressants such as Demerol and Halcion
Chlorpromazine (Thorazine)
Digoxin (Lanoxin)
Drugs for high blood pressure such as Catapres and Wytensin
Other antidepressants such as Prozac and Norpramin
Phenytoin (Dilantin)
Warfarin (Coumadin)

Special information if you are pregnant or breastfeeding

The effects of Desyrel during pregnancy have not been adequately studied. If you are pregnant or planning to become pregnant, inform your doctor immediately. This medication may appear in breast milk. If treatment with this drug is essential to your health, your doctor may advise you to discontinue breastfeeding your baby until your treatment is finished.

Recommended dosage for Desyrel

ADULTS

The usual starting dosage is a total of 150 milligrams per day, divided into 2 or more smaller doses. Your doctor may increase your dose by 50 milligrams per day every 3 or 4 days. Total dosage should not exceed 400 milligrams per day, divided into smaller doses. Once you have responded well to the drug, your doctor may gradually reduce your dose. Because this medication makes you drowsy, your doctor may tell you to take the largest dose at bedtime. CHILDREN

The safety and effectiveness of Desyrel have not been established in children below 18 years of age.

Overdosage of Desyrel

Any medication taken in excess can have serious consequences. An overdose of Desyrel in combination with other drugs can be fatal.

• Symptoms of a Desyrel overdose may include: Breathing failure, drowsiness, irregular heartbeat, prolonged, painful erection, seizures, vomiting

If you suspect an overdose, seek medical attention immediately.

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