I recently read an impassioned plea from a doctor for health care professionals to stop referring to drug by their brand name. The brand name, he argued, was basically just an advertisement for the drug. This got me to thinking, how do drugs get their names anyway? The answer is marketers, researchers, doctors, focus groups, the FDA and about $2 million. Really.

Antipsychotic medications were so named as they were initially used to treat psychosis in disorders like schizophrenia. Antipsychotics include medications like Haldol, Thorazine, Seroquel, Abilify and Zyprexa. These medications are now being used, more and more, in the treatment of other disorders like bipolar disorder and major depression. One of the major problems with these medications is a side effect called tardive dyskinesia. Tardive dyskinesia is a disorder involving involuntary muscle spasms and can be (but isn’t always) permanent – even if the medication is discontinued. How can you and your doctor look for the signs of tardive dyskinesia?

I’m a science gal. I practically drown in the stuff. True, I have a natural curiosity for pretty much everything, but also, I try to keep abreast of what’s happening in the research areas of mood disorders and psychopharmacology. Yes, it’s a lot of work. I certainly don’t catch everything, but one thing I did catch a while back was this, “Study Finds No Difference In Nonsuicide Mortality Between Two Anti-Psychotic Drugs.” Basically, neither Zyprexa nor Geodon will kill you more. But is that actually what the study showed?

As I mentioned last time, many doctors feel that antidepressants actually make bipolar disorder worse. Some specialists, in fact, will routinely take people with bipolar disorder off of antidepressants when the bipolar is doing well. Like I said, it’s a matter of perspective. And I get asked all the time about getting off of antidepressants and other medication. So, exactly how should you get off an antidepressant and what should you worry about when doing so?

While many people with bipolar disorder have and continue to be treated with antidepressants along with many other medications, there is a controversy in the medical community as to whether this is an appropriate approach. In bipolar disorder there is some risk of antidepressants inducing mania or perhaps worsening rapid-cycling. But is this true? What evidence is there that antidepressants work in bipolar disorder? What evidence is there that they will make bipolar disorder worse? What do you do if you can’t take an antidepressant?

I recently received a comment regarding bipolar medication, its development and the mental health care system in general. The commenter accuses the mental health community of being corrupt and asks, “Why are we forced to take such bad bipolar medicines?”

Let me just come right out and say it: psychiatric medications suck. They just do. Waking up every morning with your first thought to choking down brightly-colored circles, ovals and squares is a bad way to start the day. Similarly, having your last act at night be downing medication to induce what used to be the natural process of sleep is equally unfortunate. But psychiatric medications are a reality for people with a mental illness. They are important. In fact, for many of us, without them we would have no chance at a life at all. So if we admit we hate them, but admit we have to take them, how does one manage to stay on psychiatric medications?

If you’ve been diagnosed with a major mental illness, you’re probably not leaving the doctor’s office without a prescription in-hand. There’s a good reason for this: people only get help when they’re in bad shape. When people are in bad shape, medications work the most quickly and the most reliably (except electroconvulsive therapy, but that isn’t generally a first-line treatment for a host of reasons). So, if you’ve just been handed you first prescription with incomprehensible handwriting and a drug name with too many syllables, what’s a person to do? Well, you can start by following these Psych Med Commandments.

One night in 2007, I started a new antipsychotic. It was to be taken at dinner time. I did as told and took it at the universal dinner time of 6 pm. By 7 pm, I had mostly lost touch with reality. I was suddenly so tired that my eyes wouldn’t open but I was far too anxious, scared and twitchy to go to sleep. I felt incredibly ill. I was frantic, terrified and panicked. I was thrashing in a sharp, steel cage between sleep and wake with no way out. I cannot express to you the horror of that night. Bipolar medication side effects suck.

Last week I talked about Seroquel indications and dosage as well as the warnings and precautions for Seroquel. Today I complete discussion of the prescribing information on Seroquel and suggest why you need to know this stuff anyway.